Zipline Application Paths

All applications submitted in Zipline follow one of three review paths. Selecting the correct path before starting your application helps avoid delays and rework.

If you are unsure which path applies to your study, consult HSD by emailing hsdrely@uw.edu before starting.

Option 1: ÌìÃÀÓ°ÔºReviewing for ÌìÃÀÓ°ÔºOnly

Choose this option if:

  • The research may be exempt (HSD must make this determination), and/or
  • The research involves only the ÌìÃÀÓ°Ôº, or
  • Other institutions are involved, but ÌìÃÀÓ°Ôºwill not review on their behalf (for example, the ÌìÃÀÓ°ÔºIRB generally does not review for the VA).

Key points:

  • Does your project require review? Depending on the particulars of your project, you may not need to submit an IRB application.
  • Most student applications use this pathway. Visit HSD’s Getting Started page to learn more about additional requirements for student PIs.

Next step:

Option 2: ÌìÃÀÓ°ÔºReviewing for Other Institutions

Choose this option if:

Key points:

  • HSD must agree in advance to review for other institutions and establish reliance agreements
  • Approval under this path does not approve all sites at once
  • Each relying institution goes through a separate site review and receives a separate site approval

Common examples:

  • ÌìÃÀÓ°Ôºis the primary recipient of a federal award for a multi site NIH grant
  • Collaborations with local partners (e.g., Seattle Children’s or Fred Hutch) where ÌìÃÀÓ°Ôºis the primary awardee
  • International studies where ÌìÃÀÓ°Ôºis the primary recipient of a federal award

Next steps:

Option 3: Non-ÌìÃÀÓ°ÔºIRB Reviewing

Choose this option if:

  • The research requires IRB review and
  • ÌìÃÀÓ°Ôºshould not serve as the reviewing IRB.

Key points:

  • HSD must agree in advance to cede IRB review and establish reliance agreements

Common examples:

  • An external IRB is designated by the sponsor
  • The study is industry sponsored
  • ÌìÃÀÓ°Ôºis participating as a relying site in a multi site study

Next steps: